Copper Based Biomimetic Catalysts of Catechol Oxidase: An Overview on Recent Trends

The trend of modelling native enzymes is increasing day by with the motive mechanistic elucidation enzyme-catalyzed reactions and efficiency catalysts. Most metalloenzymes are capable to activate molecular oxygen due presence metal ions. Among these, copper-based metalloenzyme catechol oxidase has an attractive feature its oxidizing ability generate ortho-quinones from catechol. Moreover, conversion important tool for determination hormonally active catecholamines such as adrenaline, noradrenaline, dopa. Nevertheless, use highly expensive employment biomimetic models can be best alternative. This review summarizes some widely used methods their successful applications. Additionally, we also briefly elucidated structure-activity relationship, kinetic studies catalytic oxidation substrate, different external actors influencing cycle pH, temperature, etc.